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Commas Indicated by Key Words

 A comma must be used with coordinating conjunctions between two independent clauses.

  • You put up a good fight, but Nancy put up some really groovy wallpaper.
  • We dine at five, for we have a ball to attend this evening.
  • The television is on the fritz, so we are going to whack it with a baseball bat. 
TIP: In order for the comma to be needed with the conjunction, it must be joining two independent clauses. In other words, there must be a subject + verb before and after the conjunction for a comma to be needed.

A comma follows the exclamatory "Oh" but not the direct address "O."

  • Oh, how ludicrous that sounds!
  • O gentle king, have pity on a poor charwoman's soul! 
Parenthetical expressions starting with not should be set off by commas.
  • The thistles in my pie, not the strawberries, are making my tongue hurt.
  • I came to you, not for a lecture, but for your help.
When a series concludes with etc., the etc. is set off by commas.
  • At the Salad-o-Rama, we filled our shopping basket with lettuce, tomatoes, carrots,etc., but no croutons. 
A comma is used to set off terms such as that is, namely, i.e., and e.g. when they are used to introduce a series or an example.
  • Some students, namely, Morticia, Gilligan, and Dano, had better practice their brainstorming skills. 
  • I suggest you leave right now,i.e., beat it, if you know what's good for you.
A comma is used to set off conjunctive adverbs
  • Your application has been denied; however, we will keep it in mind for future consideration. 
TIP: Don't forget that when you join two independent clauses with conjuctive adverbs, you must seperate the clauses with a semicolon, then follow the adverb with a comma!